Human stem cells were recently used at the University of Sydney to treat pain in mice. The study proved there were no lasting side effects and are planning to test this on rodents and pigs before human testing. If the following tests are successful, stem cell treatment poses as a non-addictive alternative to relieving pain without the use of opioids.
Associate Professor Greg Neely, a leader in pain research at the Charles Perkins Centre and the School of Life and Environmental Sciences mentions, “Nerve injury can lead to devastating neuropathic pain and for the majority of patients, there are no effective therapies. This breakthrough means for some of these patients, we could make pain-killing transplants from their own cells, and the cells can then reverse the underlying cause of pain.”
Researchers used human induced pluripotent stem cells (iPSC) extracted from bone marrow to produce pain-killing cells in the lab. They then put them into the spinal cord of mice suffering intense pain. Scientists found these neuron transplants survive long term in the injured spinal cord. This creates an opportunity for synaptic integration for effective pain treatment.
The development of iPSC won a Nobel Prize in 2012 and for this study, stem cells were taken from human blood samples.
“Because we can pick where we put our pain-killing neurons, we can target only the parts of the body that are in pain. This means our approach can have fewer side effects,” adds John Manion, a Ph.D. student and lead author of the study.
Lack of effective pain treatment has grown into seeking management alternatives in opioids. According to the Centres for Disease Control and Prevention, more than two million Americans currently abuse or are dependent on opioids.
With the opioid epidemic claiming the lives of many and affecting families, it’s exciting to see non-addictive and less expensive alternatives on the rise.
If we have added value to your life and you want to support us and become more involved with what we do you can now become an
You can follow us on Instagram HERE
Please subscribe to our YouTube channel HERE.
Follow Us :
- Animals9 months ago
German Circus Uses Holograms Instead Of Live Animals For A Cruelty-Free Magical Experience
- Environment5 months ago
Bars In Italy Are Starting To Use Pasta Straws To Reduce Plastic Waste
- Nature2 years ago
A woman photographed ancient trees for 14 years, and here are the results
- Animals1 year ago
The Zoo That Puts People In Moving Cages While Animals Roam Free
- Environment4 months ago
Forest Garden With 500 Edible Plants Requires Only a Few Hours of Work Per Month
- Meditation1 year ago
1 Million Children Get Together And Meditated For World Peace In Thailand
- America3 months ago
Bon Jovi Opened 2 Restaurants That Allow People In Need To Eat Free Of Charge
- Science & Technology3 years ago
If You’re Annoyed By Others Chewing, You May Be A Genius